Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 180 Veggie Caps

4.5

Price: $23.59

Sold by Vitap

Standard Shipping $4.5 on orders shipped from Vitap

Delivery order Estimated Sep 26 - Sep 30
Courier company: USPS USPS , Fedex Fedex , UPS UPS , DHL Express DHL Express , Etc...

Return Policy

You can return it to us within 3 days after delivery or 30 days after shipment in case the delivery date is not traceableView More

  • DOCTOR’S BEST MSM FEATURES OPTIMSM: with OptiMSM a high quality purified MSM (methylsulfonylmethane) backed by numerous clinical studies for safety and efficacy. MSM is a natural sulfur compound that helps support the formation of healthy connective tissues.
  • BENEFITS TO JOINTS: MSM is a natural sulfur that helps form the antioxidants N-acetylcysteine and glutathione and serves as a key structural nutrient in healthy joints. Improves joint function and helps protect cartilage, mobility, reduces joint pain, increases range of motion.
  • IMMUNE SUPPORT: MSM provides support for immune function, and for the body’s antioxidant and overall protective capacities resulting in a stronger immune response.
  • NATURE’S BEAUTY MINERAL: MSM provides sulfur and is often called “nature’s beauty mineral”. Sulfur restores collagen production that supports healthy skin and is a building block of keratin, an essential protein for improving skin, hair and nails.
  • CLINICAL STUDIES: Sulfur continues to be an important dietary nutrient to support healthy aging. With its regulation of glutathione and other ways in the body, MSM can help support healthy skin, joint mobility, cartilage, and the antioxidant response.
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers’ recommendations, when provided.

Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 180 Veggie Caps

Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 180 Veggie Caps

Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 180 Veggie Caps

Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 180 Veggie Caps

Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 180 Veggie Caps

Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 180 Veggie Caps

Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 180 Veggie Caps

Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 180 Veggie Caps

Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 180 Veggie Caps

Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 180 Veggie Caps


From the manufacturer

FDA Statement:

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Best MSM supplies highly purified MSM (methylsulfonylmethane), a compound notable for its methyl groups (required for numerous metabolic functions) and the conditionally essential mineral sulfur, which is a crucial component of powerful antioxidants such as N-acetylcysteine and glutathione. Although MSM occurs naturally in some foods and in the human body at low concentrations, a significant amount of MSM is lost during the heating and processing of foods.

What are the benefits of MSM?

– Helps promote joint comfort and mobility.*

– Helps support healthy immune response.*

– Helps enhance antioxidant defenses.*

Why take MSM?

– MSM may help form, reinforce, and protect healthy joint tissue throughout the body.*

– MSM is a natural sulfur that helps form the antioxidants N-acetylcysteine and glutathione and serves as a key structural nutrient in healthy joints.

– Since MSM enhances keratin, MSM offers additional support for healthy hair and nails.*

How does it work?

– MSM’s supports the disulfide bonds that reinforce collagen fibers, a property that’s believed to promote tissue integrity and resilience.

– Laboratory research suggests MSM can help regulate free radical production by neutrophils (white blood cells in the body.*

Promotes joint comfort and mobility.*

In a double blind, placebo-controlled trial, 50 men and women were randomized to receive either 3,375 mg (3.375 grams) of MSM or a placebo daily for 12 weeks.7 Participants were instructed to take the tablets (each was 1.125 grams) in three doses per day with food, and to avoid taking the tablets before bed. Several validated and reliable scoring methods were used to measure joint function and comfort during the study. Compared with placebo, MSM was shown to significantly promote joint function and comfort, without side effects.

A larger dose was used in a randomized, double blind, placebo-controlled trial of 50 men and women (ages 40–76).8 Participants were randomized into two groups to receive either placebo capsules or OptiMSM in 1 gram capsules for 12 weeks. They were instructed to ramp up to the eventual dose of 6 grams per day by starting with two doses of 2 grams per day for 3 days, followed by an increase to 4 grams per day for the next 4 days. At the beginning of the second week, the dose was raised to 3 grams twice daily. Participants were instructed to take the MSM with food, and to avoid taking it at bedtime. Knee joint function and comfort were measured by standardized (reliable and valid) questionnaires. After 12 weeks, physical function and knee joint comfort were shown to be superior in the MSM group when compared to placebo.

In a more complex double blind study, MSM was tested versus (a) a placebo, (b) glucosamine, and (c) a combination of MSM with glucosamine, in 118 men and women (ages 40–70).9 Participants were randomized into four groups to receive either a placebo, MSM alone (500 mg three times daily), glucosamine alone (500 mg three times daily), or MSM + glucosamine (500 mg each, three times daily). Using a number of analytical tools that measured joint functionality, comfort, and quality of life related to joint health, the researchers found that the MSM and glucosamine groups experienced significant support for joint health, whereas the placebo group experienced no such benefits. Additionally, the combination of MSM + glucosamine was significantly better at promoting joint comfort and functional ability than either taken alone.

MSM could serve as a source of sulfur to support the maintenance and formation of cartilage, thereby supporting knee joint health.10 Its two methyl groups could be valuable to its actions, being necessary for tissue repair and maintenance. Its molecular structure suggests it could also have redox (electronic catalytic) properties that would facilitate antioxidant or other human benefits.

Enhances antioxidant defenses.*

Supports healthy immune response.*

Oxidative stress is a term used to describe negative imbalance between production of reactive oxygen species (ROS) and the body’s antioxidant capacities. Strenuous exercise have the potential to create an uptick of ROS, and subsequently oxidative stress.11 Human and animal studies suggest that taking MSM prior to exercise may help to ease oxidative stress, especially in individuals not accustomed to the stress of exercise.12, 13.

MSM has been suggested to support healthy immune function through antioxidant actions. Neutrophils, the most abundant white blood cells in the body, routinely release free radicals crucial to their immune activities; this can be a double-edged sword, as excessive free radical generation contributes to oxidative stress. Laboratory research suggests MSM can help regulate free radical production by neutrophils.14 In mice macrophage (immune) cells, MSM was shown to down-regulate overactive immune factors without being toxic to the cells.15 In a mouse model examining joint health, MSM dissolved in the drinking water influenced immune function in a way that significantly supported joint structure and function when compared to mice in a control group.16.

While new research is exploring the potential of methylsulfonylmethane in promoting the maintenance of GI health18 and bone health,19 the current clinical evidence shows MSM provides meaningful support for the joints, for immune function, and for the body’s antioxidant and overall protective capacities. MSM is proven very safe to take, very well tolerated, and effective at intakes as high as 6000 mg (6 grams) per day.

Scientific References:

1. Monograph. Altern Med Rev 2003;8:438-41.

2. Parcell S. Altern Med Rev 2002;7:22-44.

3. Lovelock JE, Magga RJ. Nature 1972;237:452-453.

4. Jacob SW, Herschler R. Annals of the NY Acad Sci 1983;411:xiii-xvii.

5. Pearson TW, Dawson HJ, Lackey HB. J Agric Food Chem 1981;29:1089-91.

6. Silva Ferreira AC, Rodrigues P, Hogg T, Guedes De Pinho P. J Agric Food Chem 2003;51:727-32.

7. Debbi EM, Agar G, Fichman G, others. BMC Complement Altern Med 2011;11:50.

8. Kim LS, Axelrod LJ, Howard P, others. Osteoarthritis Cartilage 2006;14:286-94.

9. Usha PR, Naidu MU. Clin Drug Investig 2004;24:353-63.

10. Ezaki J, Hashimoto M, Hosokawa Y, Ishimi Y. J Bone Miner Metab 2013;31:16-25.

11. Fisher-Wellman K, Bloomer RJ. Dyn Med 2009;8:1.

12. Kalman DS, Feldman S, Scheinberg AR, others. J Int Soc Sports Nutr 2012;9:46.

13. Maranon G, Munoz-Escassi B, Manley W, others. Acta Vet Scand 2008;50:45.

14. Beilke MA, Collins-Lech C, Sohnle PG. J Lab Clin Med 1987;110:91-6.

15. Kim YH, Kim DH, Lim H, others. Biol Pharm Bull 2009;32:651-6.

16. Hasegawa T, Ueno S, Kumamoto S, Yoshikai Y. Jpn Pharmacol Ther 2004;32.

17. Barrager E, Veltmann JR, Jr., Schauss AG, Schiller RN. J Altern Complement Med 2002;8:167-73.

18. Amirshahrokhi K, Bohlooli S, Chinifroush MM. Toxicol Appl Pharmacol 2011;253:197-202.

19. Joung YH, Lim EJ, Darvin P, others. PLoS One 2012;7:e47477.


Product Description

Best MSM features Optimism, a highly purified form of methylsulfonyl methane (MSM). Also known as methyl sulfone or dimethyl sulfone (DMSO2), MSM contains two oxygen atoms and two methyl groups bound to a sulfur atom. The sulfur, which makes up about 34% of the elemental weight of MSM, is a part of the global sulfur cycle that results in plants taking up MSM from the rain and becoming a concentrated source of the compound. Unlike its parent compound dimethylsulfoxide (DMSO), MSM doesn’t contribute to unpleasant after-effects such as garlic-like breath. Methylsulfonylmethane is widely distributed in nature and found in trace quantities among many foods, and in relatively higher quantities in a few foods and beverages, most notably Swiss chard, concentrated tomato products, milk, coffee, beer, port wine, and tea. Since the amount of MSM found naturally in living materials is too small to be extracted, the MSM used for dietary supplements is manufactured. The makers of Optimism developed a four-stage process to separate impurities including heavy metals and other contaminants from Optimism. Each batch exceeds the United States Pharmacopeia (USP) monograph standards for MSM, and is validated by testing in independent laboratories.



Flavor

Unflavored

Primary Supplement Type

mineral

Unit Count

180 Count

Item Form

Capsule

Item Weight

0.55 Pounds

Item Dimensions LxWxH

3.13 x 3.13 x 5.19 inches

Special Ingredients

Methylsulfonylmethane

Diet Type

Gluten Free

Product Benefits

Bone & Joint Support


Product reviews